[NewPacifica] MInd control/Schizophrenia/ Haldol Implant Debate



http://www.boston.com/yourlife/health/mental/articles/2003/09/26/drug_implant_offers_hope_spurs_worry

This article says that the implant can last up to a year. I am wondering what 
happens if the medication has side effects and you are stuck with it for a 
year. People are worried about this implant because they are afraid the the 
court can force it on you in cases. I know I don't want an implant or the depot 
injections. I like to be able to switch meds when they have side effects. They 
already have shots that can last a month. I am just thinking with the side 
effects and risks, weight gain, diabetes, elevated prolactin levels, akathisia 
that a year being on a farked up med is a long time. Maybe they can remove the 
implant. Also, if the person has delusions that there are spy body implants 
wouldn't a med implant be scary. If the person had insight into their having 
schizophrenia it would be one thing. I am not trying to talk stupid, I am just 
saying you get get paranoid ideas about an implant inside you.----Melinda =^..^=

Here is another article on it:
http://www.centredaily.com/mld/centredaily/news/6896626.htm
Implant could help schizophrenics stay medicated, raises ethical concerns
BY STACEY BURLING
Knight Ridder Newspapers

PHILADELPHIA - (KRT) - Do a Google search on the words "implant" and "mind 
control" and you'll get about 100,000 hits, a virtual primer on conspiracy 
theories and science-fiction nightmares.

So it's no surprise that when the University of Pennsylvania announced that one 
of its scientists was perfecting an implant that could provide a year's worth 
of medication for people with severe mental illness, it was met in some 
quarters with distrust.

David Oaks, executive director of Support Coalition International, which 
questions the dominant view that mental illnesses are biological at base, for 
example, calls the device "inherently coercive."

Aware of the concerns, the university took the unusual step last week of 
inviting representatives of consumer-advocacy groups to a symposium on the 
ethical implications of the implants well before they are ready for marketing.

Paul Root Wolpe, a Penn ethicist who took part in the meeting, said he saw it 
as an opportunity for disparate groups to help set the ground rules for how a 
promising new treatment would be used.

"If we agree that this technology has a potential for misuse, and I really 
think it does, we can build coalitions to prevent that," he said.

Researcher Steven Siegel, a psychiatrist and neurobiologist, conceived of the 
biodegradable implants as a way to solve a problem that has persistently 
plagued treatment of people with schizophrenia, the most serious of the mental 
illnesses. A high percentage stop taking their medications and almost 
inevitably descend into disorganized thinking, hallucinations and delusions 
that can leave them jobless, friendless and homeless.

The implants, he said, have the potential to give people with serious mental 
illnesses the stability they need to develop long-term friendships and careers. 
The technology could be used with many drugs, including those for treating 
other chronic illnesses. Studies show that half the people with all sorts of 
diseases fail to take their medicines consistently.

Siegel's team at Penn so far has tested the implants - quarter-size devices 
containing polymers made of lactic acid and glycolic acid fused with 
haloperidol (Haldol) - in mice, rats, rabbits and monkeys. Siegel thinks the 
Food and Drug Administration will require at least one more round of 
animal-testing, possibly in dogs, before considering approval, so the implants 
are probably a year or two away from human-testing. The implants are placed 
under the skin during a 15-minute surgical procedure and can be removed.

Aside from the obvious advantage that patients could not forget to take their 
medication while using the implant, Siegel said that delivering the drug under 
the skin makes lower doses possible and may reduce side effects.

The biggest concern about the implants is that they would be forced upon 
patients and that it would be difficult for patients to change their minds. 
Volpe and patients worried that the criminal-justice system, in particular, 
would coerce patients to take the drugs. How much choice would people really 
have, they asked, if they were told that they could either have an implant or 
go to jail, or that they wouldn't be allowed to leave the hospital until they 
accepted an implant?

Patients and others also worried that managed-care companies might find the 
implants more attractive than current approaches that require more monitoring. 
The result could be that patients would see their psychiatrists less often, 
harming the doctor-patient relationship.

With minimal precedent and multiple arenas of concern - pharmacological, legal, 
sociological - broadly accepted protocols will not happen quickly.

Siegel says the implant would only be an option for stable, rational patients 
who chose to take their medicine this way. "This is a medicine like any other 
medicine," he said. "We don't give people medicine when they say no."

While he made an effort to invite potential critics to last week's meeting, 
most of his calls and e-mails about the implants have been supportive, he said. 
"Overwhelmingly, it's, `When can I have this? When can my son have this?' "
-- 
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